Immunoactivating conjugates comprising nanoparticles coated with peptides

V. Franco Puntes, N. Gómez Bastús, E. Sánchez Tilló, C. Farrera Sinfreu, A. Celada Cotarelo, J. Lloberas Cavero, E. Giralt Lledó, S. Pujals Riatós.

Institut Català de Nanotecnologia (ICN), Institució Catalana de Recerca i Estudis Avançats (ICREA), Universitat de Barcelona (UB), Institut de Recerca Biomèdica.

Reference papers:

  • Bastus, N., Sanchez-Tillo, E., Pujals, S., Farrera, C., Kogan, M., Giralt, E., Celada, A., Lloberas, J., & Puntes, V. (2009). Peptides conjugated to gold nanoparticles induce macrophage activation. Molecular Immunology, 46(4), 743–748.
  • Bastús, N. G., Sánchez-Tilló, E., Pujals, S., Farrera, C., López, C., Giralt, E., Celada, A., Lloberas, J., Puntes, V. (2009). Homogeneous Conjugation of Peptides onto Gold Nanoparticles Enhances Macrophage Response. ACS Nano, 3(6), 1335–1344.

Patent info: Patent No. WO 2010/046377 (Priority date: October 23, 2008) [Status: Public]

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